T0410

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T0410

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Tiapride hydrochloride

Synonym:N-[2-(Diethylamino)ethyl]-5-(methylsulfonyl)-o-anisamide hydrochloride
CAS Number:51012-32-9
Linear Formula:C15H24N2O4S · HCl
Molecular Weight:364.89
EC Number:256-908-4
MDL number:MFCD00133861
PubChem Substance ID:24278720

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Description

Biochem/physiol ActionsD2 and D3 dopamine receptor antagonist; antipsychotic.

Properties

Gene Informationhuman ... DRD2(1813), DRD3(1814)
storage temp.2-8°C

Safety

Personal Protective EquipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
WGK Germany2
RTECSCV4203800

References

referenceLidow and Goldman-Rakic, Differential regulation of D2 and D4 dopamine receptor mRNAs in the primate cerebral cortex vs. neostriatum: effects of chronic treatment with typical and atypical. J. Pharmacol. Exp. Ther. 283, 939, (1997) Abstract
 Peters and Faulds, Tiapride, A review of its pharmacology and therapeutic potential in the management of alcohol dependence syndrome. Drugs 47, 1010, (1994) Abstract
 Cohen, et al., Characterization of the discriminative stimulus produced by the dopamine antagonist tiapride. J. Pharmacol. Exp. Ther. 283, 566, (1997) Abstract